NAV1 Antikörper (AA 1426-1475)

Produktnummer ABIN1386327

Dieser Anti-NAV1 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von NAV1 in WB, ELISA, IF (cc), IF (p), IHC (fro), IHC (p) und ICC. Geeignet für Human.

Kurzübersicht für NAV1 Antikörper (AA 1426-1475) (ABIN1386327)

Target: NAV1 (Neuron Navigator 1 (NAV1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NAV1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunocytochemistry (ICC)

Produktdetails anti-NAV1 Antikörper

Bindungsspezifität: AA 1426-1475

Homologie: Human,Mouse,Rat,Dog,Pig,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Neuron navigator 1

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200
ICC 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Details zu NAV1

Target: NAV1 (Neuron Navigator 1 (NAV1))

Andere Bezeichnung: Neuron navigator 1

Hintergrund:

Synonyms: Nav 1, Nav1, POMFIL 3, POMFIL3, Pore membrane and/or filament interacting like protein 3, Protein Steerin 1, Protein Steerin1, Steerin 1, Steerin1, unc-53 homolog 1, DKFZp781D0314, FLJ12560, FLJ14203, mNav1, NAV1_HUMAN.

Background: Neuron navigator 1 is a 1877 amino acid cytoplasmic protein that is involved in neuronal migration. Neuron navigtor 1 is widely expressed at low levels, though highest expression is found in both adult and fetal nervous tissue. Through interaction with tubulin, Neuron navigator 1 associates with a subset of mirotubule plus ends present in the growth cone. Overexpression of Neuron navigator 1 leads to microtubule bundling, whereas a reduction of its levels causes loss of directionality in the migration of pontine cell leading processes. There are seven isoforms of Neuron navigator 1 that are produced as a result of alternative splicing events.